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Livres
Articles (64)
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Foamy Virus Vectors for HIV Gene Therapy

Olszko, Miles, Trobridge, Grant

Journal:

Viruses

Année:

2013

Langue:

english

Fichier:

PDF, 572 KB

english, 2013

Large Animal Models for Foamy Virus Vector Gene Therapy

Trobridge, Grant, Horn, Peter, Beard, Brian, Kiem, Hans-Peter

Journal:

Viruses

Année:

2012

Langue:

english

Fichier:

PDF, 260 KB

english, 2012

Interferon-inducible Mx proteins in fish

Jo-Ann C. Leong, Grant D. Trobridge, Carol H. Y. Kim, Marc Johnson, Ben Simon

Journal:

Immunological Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 8.05 MB

english, 1998

Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells

Nina M. Muñoz, Grant D. Trobridge, Hans-Peter Kiem

Journal:

Journal of Medical Primatology

Année:

2009

Langue:

english

Fichier:

PDF, 210 KB

english, 2009

A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells

Hans-Peter Kiem, Christina Ironside, Brian C. Beard, Grant D. Trobridge

Journal:

Experimental Hematology

Année:

2010

Langue:

english

Fichier:

PDF, 2.47 MB

english, 2010

Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model

Korashon L. Watts, Veronica Nelson, Brent L. Wood, Grant D. Trobridge, Brian C. Beard, R. Keith Humphries, Hans-Peter Kiem

Journal:

Experimental Hematology

Année:

2012

Langue:

english

Fichier:

PDF, 780 KB

english, 2012

Molecular cloning of double-stranded RNA inducible MX genes from atlantic salmon (Salmo salar l.)

Børre Robertsen, Grant Trobridge, Jo-Ann Leongt

Journal:

Developmental & Comparative Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 1.36 MB

english, 1997

G12 2:00 Cytokines and their use in the vaccination of fish

Jo-Ann Leong, Eric Anderson, Marc Johnson, Carol Kim, Dan Mourich, Grant Trobridge

Journal:

Developmental & Comparative Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 96 KB

english, 1997

S1 10:00 Immune response to viral diseases in fish

Jo-Ann C. Leong, Linda Bootland, Pinwen C. Chiou, Barbara Drolet, Marc Johnson, Carol Kim, Dan Mourich, Kunio Suzuki, Grant Trobridge

Journal:

Developmental & Comparative Immunology

Année:

1997

Langue:

english

Fichier:

PDF, 71 KB

english, 1997

Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities

Adair, Jennifer E., Zhao, Xin, Chien, Sylvia, Fang, Min, Wohlfahrt, Martin E., Trobridge, Grant D., Taylor, Jason A., Beard, Brian C., Kiem, Hans-Peter, Becker, Pamela S.

Journal:

Journal of Molecular Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 634 KB

english, 2012

AMP-activated protein kinase stimulates myostatin expression in C2C12 cells

Arun K. Das, Qi-Yuan Yang, Xing Fu, Jun-Fang Liang, Marcio S. Duarte, Mei-Jun Zhu, Grant D. Trobridge, Min Du

Journal:

Biochemical and Biophysical Research Communications

Année:

2012

Langue:

english

Fichier:

PDF, 635 KB

english, 2012

CD34+ Expansion With Delta-1 and HOXB4 Promotes Rapid Engraftment and Transfusion Independence in a Macaca nemestrina Cord Blood Transplant Model

Watts, Korashon L, Delaney, Colleen, Nelson, Veronica, Trobridge, Grant D, Beard, Brian C, Humphries, R Keith, Kiem, Hans-Peter

Journal:

Molecular Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 660 KB

english, 2013

Differential Effects of HOXB4 and NUP98-HOXA10hd on Hematopoietic Repopulating Cells in a Nonhuman Primate Model

Watts, Korashon L., Zhang, Xiaobing, Beard, Brian C., Chiu, Sum Ying, Trobridge, Grant D., Humphries, R. Keith, Kiem, Hans-Peter

Journal:

Human Gene Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 377 KB

english, 2011

Hematopoietic Stem Cell Transduction and Amplification in Large Animal Models

Trobridge, Grant, Beard, Brian C., Kiem, Hans-Peter

Journal:

Human Gene Therapy

Année:

2005

Langue:

english

Fichier:

PDF, 175 KB

english, 2005

Effect of Fetal Bovine Serum on Foamy and Lentiviral Vector Production

Powers, John M., Trobridge, Grant D.

Journal:

Human Gene Therapy Methods

Année:

2013

Langue:

english

Fichier:

PDF, 181 KB

english, 2013

Allogeneic Transplantation, Fas Signaling, and Dysregulation of Hepcidin

Li, Xiang, Xu, Feng, Karoopongse, Ekapun, Marcondes, A. Mario, Lee, Kayoung, Kowdley, Kris V., Miao, Carol H., Trobridge, Grant D., Campbell, Jean S., Deeg, H. Joachim

Journal:

Biology of Blood and Marrow Transplantation

Année:

2013

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2013

No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model

Watts, Korashon L., Beard, Brian C., Wood, Brent L., Trobridge, Grant D., Humphries, R. Keith, Adams, Amie B., Nelson, Veronica, Kiem, Hans-Peter

Journal:

Experimental Hematology

Année:

2014

Langue:

english

Fichier:

PDF, 17.40 MB

english, 2014

A novel approach to identify driver genes involved in androgen-independent prostate cancer

Schinke, Ellyn N, Bii, Victor, Nalla, Arun, Rae, Dustin T, Tedrick, Laura, Meadows, Gary G, Trobridge, Grant D

Journal:

Molecular Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 399 KB

english, 2014

Characterization of a Rainbow Trout Mx Gene

TROBRIDGE, GRANT D., LEONG, JO-ANN C.

Journal:

Journal of Interferon & Cytokine Research

Année:

1995

Langue:

english

Fichier:

PDF, 4.82 MB

english, 1995

Genotoxicity of retroviral hematopoietic stem cell gene therapy

Trobridge, Grant D

Journal:

Expert Opinion on Biological Therapy

Année:

2011

Langue:

english

Fichier:

PDF, 442 KB

english, 2011

Gene Targeting by Adeno-Associated Virus Vectors Is Cell-Cycle Dependent

Trobridge, Grant, Hirata, Roli K., Russell, David W.

Journal:

Human Gene Therapy

Année:

2005

Langue:

english

Fichier:

PDF, 105 KB

english, 2005

Unique Integration Profiles in a Canine Model of Long-Term Repopulating Cells Transduced with Gammaretrovirus, Lentivirus, or Foamy Virus

Beard, Brian C., Keyser, Kirsten A., Trobridge, Grant D., Peterson, Laura J., Miller, Daniel G., Jacobs, Michael, Kaul, Rajinder, Kiem, Hans-Peter

Journal:

Human Gene Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 278 KB

english, 2007

Genetic manipulation of myoblasts and a novel primary myosatellite cell culture system: comparing and optimizing approaches

Jackson, Melissa F., Hoversten, Knut E., Powers, John M., Trobridge, Grant D., Rodgers, Buel D.

Journal:

FEBS Journal

Année:

2012

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2012

Efficient Generation of Nonhuman Primate Induced Pluripotent Stem Cells

Zhong, Bonan, Trobridge, Grant D., Zhang, Xiaobing, Watts, Korashon L., Ramakrishnan, Aravind, Wohlfahrt, Martin, Adair, Jennifer E., Kiem, Hans-Peter

Journal:

Stem Cells and Development

Année:

2011

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2011

Stable Marking and Transgene Expression Without Progression to Monoclonality in Canine Long-Term Hematopoietic Repopulating Cells Transduced with Lentiviral Vectors

Enssle, Joerg, Trobridge, Grant D., Keyser, Kirsten A., Ironside, Christina, Beard, Brian C., Kiem, Hans-Peter

Journal:

Human Gene Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2010

Foamy and Lentiviral Vectors Transduce Canine Long-Term Repopulating Cells at Similar Efficiency

Trobridge, Grant D., Allen, James, Peterson, Laura, Ironside, Christina, Russell, David W., Kiem, Hans-Peter

Journal:

Human Gene Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 4.58 MB

english, 2009

372. Optimizing Foamy Virus Vectors That Inhibit HIV Infection

Taylor, Jason A., Vojtech, Lucia, Olson, Erik M., Allen, James M., Trobridge, Grant D., Russell, David W., Richard, Robert E.

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 107 KB

english, 2006

Helper-Free Foamy Virus Vectors

Trobridge, Grant D., Russell, David W.

Journal:

Human Gene Therapy

Année:

1998

Langue:

english

Fichier:

PDF, 270 KB

english, 1998

Transduction of Long-Term and Mobilized Peripheral Blood-Derived NOD/SCID Repopulating Cells by Foamy Virus Vectors

Josephson, Neil C., Trobridge, Grant, Russell, David W.

Journal:

Human Gene Therapy

Année:

2004

Langue:

english

Fichier:

PDF, 368 KB

english, 2004

Helper-Free Foamy Virus Vectors

Trobridge, Grant D., Russell, David W.

Journal:

Human Gene Therapy

Année:

1998

Langue:

english

Fichier:

PDF, 3.59 MB

english, 1998

Foamy virus vectors for gene transfer

Trobridge, Grant D

Journal:

Expert Opinion on Biological Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 498 KB

english, 2009

VISA - Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

Hocum, Jonah D., Battrell, Logan R., Maynard, Ryan, Adair, Jennifer E., Beard, Brian C., Rawlings, David J., Kiem, Hans-Peter, Miller, Daniel G., Trobridge, Grant D.

Journal:

BMC Bioinformatics

Année:

2015

Langue:

english

Fichier:

PDF, 538 KB

english, 2015

Cocal-pseudotyped Lentiviral Vectors Resist Inactivation by Human Serum and Efficiently Transduce Primate Hematopoietic Repopulating Cells

Trobridge, Grant D, Wu, Robert A, Hansen, Michael, Ironside, Christina, Watts, Korashon L, Olsen, Philip, Beard, Brian C, Kiem, Hans-Peter

Journal:

Molecular Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 247 KB

english, 2010

Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells

Beard, Brian C, Dickerson, David, Beebe, Kate, Gooch, Christina, Fletcher, James, Okbinoglu, Tulin, Miller, Daniel G, Jacobs, Michael A, Kaul, Rajinder, Kiem, Hans-Peter, Trobridge, Grant D

Journal:

Molecular Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 301 KB

english, 2007

Modified Genomic Sequencing PCR Using the MiSeq Platform to Identify Retroviral Integration Sites

Rae, Dustin T., Collins, Casey P., Hocum, Jonah D., Browning, Diana L., Trobridge, Grant D.

Journal:

Human Gene Therapy Methods

Année:

2015

Langue:

english

Fichier:

PDF, 238 KB

english, 2015

Insulated Foamy Viral Vectors

Browning, Diana L., Collins, Casey P., Hocum, Jonah D., Leap, David J., Rae, Dustin T., Trobridge, Grant D.

Journal:

Human Gene Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 687 KB

english, 2016

Development of 3rd Generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T Cells

Humbert, Olivier, Gisch, Don W., Wohlfahrt, Martin E., Adams, Amie B., Greenberg, Phil D., Schmitt, Tom M., Trobridge, Grant D., Kiem, Hans-Peter

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 6.43 MB

english, 2016

Lentiviral vector-mediated insertional mutagenesis screen identifies genes that influence androgen independent prostate cancer progression and predict clinical outcome

Nalla, Arun K., Williams, Theodore F., Collins, Casey P., Rae, Dustin T., Trobridge, Grant D.

Journal:

Molecular Carcinogenesis

Année:

2015

Langue:

english

Fichier:

PDF, 798 KB

english, 2015

Retroviral vector interactions with hematopoietic cells

Everson, Elizabeth M, Trobridge, Grant D

Journal:

Current Opinion in Virology

Année:

2016

Langue:

english

Fichier:

PDF, 392 KB

english, 2016

Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy

Adair, Jennifer E., Waters, Timothy, Haworth, Kevin G., Kubek, Sara P., Trobridge, Grant D., Hocum, Jonah D., Heimfeld, Shelly, Kiem, Hans-Peter

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 856 KB

english, 2016

Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes

Hocum, Jonah D., Linde, Ian, Rae, Dustin T., Collins, Casey P., Matern, Lindsay K., Trobridge, Grant D.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 479 KB

english, 2016

A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance

Everson, Elizabeth M, Olzsko, Miles E, Leap, David J, Hocum, Jonah D, Trobridge, Grant D

Journal:

Molecular Therapy — Methods & Clinical Development

Année:

2016

Langue:

english

Fichier:

PDF, 434 KB

english, 2016

6. Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-Oncogenes

Hocum, Jonah D., Linde, Ian, Rae, Dustin T., Collins, Casey P., Matern, Lindsay K., Trobridge, Grant D.

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 642 KB

english, 2016

687. Development of a Safe and Effective Combinatorial Foamy Virus Vector for HIV Gene Therapy

Nalla, Arun K., Williams, Theodore, Lemon, Athena, Qamou, Rahaf, Everson, Elizabeth, Trobridge, Grant D.

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2016

288. Development of Cocal Glycoprotein Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T Cells

Humbert, Olivier, Gisch, Donald, Wohlfahrt, Martin, Greenberg, Phil, Schmitt, Tom, Trobridge, Grant, Kiem, Hans-Peter

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 336 KB

english, 2016

284. Long-Term Therapeutic Immune Reconstitution in XSCID Canine Model via In Vivo Foamy Virus Delivery of Common Gamma Chain

Chan, Frieda, Humbert, Olivier, Burtner, Christopher, Humphrys, Daniel, Adair, Jennifer, Trobridge, Grant, O'Donnell, Patricia, Hubbard, Nicholas, Torgerson, Troy, Scharenberg, Andrew, Rawlings, David

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 268 KB

english, 2016

683. Foamy Virus Gene Therapy Significantly Restores Lymphocyte Development and Function in SCID-X1 Mice

MacQuivey, Matthew, Curinga, Gabrielle, Hubbard, Nick, Khan, Iram, Clough, Courtnee, Humphrys, Daniel, Adair, Jennifer, Trobridge, Grant, Torgerson, Troy, Scharenberg, Andy, Kiem, Hans-Peter, Rawlings

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 299 KB

english, 2016

230. A Novel Gammaretroviral Shuttle Vector Insertional Mutagenesis Screen To Identify Breast Cancer Metastasis Genes

Bii, Victor M., Rae, Dustin T., Trobridge, Grant T.

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 406 KB

english, 2015

441. Direct Comparison of EF1α and PGK Promoters Reveals Superior Performance of the PGK Promoter for Expression of the Common Gamma Chain in a Canine Model of In Vivo Foamy Virus Gene Therapy for Severe Combined Immunodeficiency

Burtner, Christopher R., Olivier, Humbert, O'Donnell, Patricia, Hubbard, Nicholas, Humphrys, Daniel, Adair, Jennifer E., Trobridge, Grant D., Torgerson, Troy R., Scharenberg, Andrew M., Rawlings, Davi

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 373 KB

english, 2015

533. A Clinically Relevant Approach for Retargeting Foamy Viral Vectors Into Heterochromatin

Hocum, Jonah D., Rae, Dustin T., Collins, Casey P., Linde, Ian, Matern, Lindsay K., Trobridge, Grant D.

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 509 KB

english, 2015